Scalable Electrochemical Transition‐Metal‐Free Dehydrogenative Cross‐Coupling Amination Enabled Alkaloid Clausines Synthesis

Abstract

Abstract Reported herein is an environmentally benign electrochemical C−H bond dehydrogenative amination protocol for the construction of privileged carbazole moiety with broad generality. Preliminary mechanistic investigations implied a radical reaction pathway. Compared with traditional ionic routes, the scalable transition‐metal and exogenous‐oxidant free strategy highlighted the green and sustainable nature of this method. magnified image