Dual peptide-dendrimer conjugate inhibits acetylation of transforming growth factor β-induced protein and improves survival in sepsis

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

Chunaram Choudhary, Chanchal Kumar, Florian Gnad et al. · Science · 2009 · 4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Immunodesign of experimental sepsis by cecal ligation and puncture

Daniel Rittirsch, Markus Huber‐Lang, Michael A. Flierl et al. · Nature Protocols · 2008 · 2.2K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +12

Drotrecogin Alfa (Activated) in Adults with Septic Shock

V. Marco Ranieri, Bruce Thompson, Philip S. Barie et al. · New England Journal of Medicine · 2012 · 1.3K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +9

The nuclear protein HMGB1 is secreted by monocytes via a non‐classical, vesicle‐mediated secretory pathway

Stefania Gardella, Cristina Andrei, Denise Ferrera et al. · EMBO Reports · 2002 · 922 citations · Full text

Life Sciences, Immunology, Molecular Biology +8

Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation

Jonathan B. Rothbard, Sarah Garlington, Qun Lin et al. · Nature Medicine · 2000 · 633 citations

Medicine, Pharmaceutics, Pharmacology +14