Concepedia

Serum neuronal exosomes predict and differentiate Parkinson’s disease from atypical parkinsonism

Cheng Jiang, Franziska Hopfner, Antigoni Katsikoudi, Robert Hein, Candan Catli, Samuel Evetts, Yongzhi Huang, Hong Wang, John Ryder, Gregor Kuhlenbäeumer,

Journal of Neurology Neurosurgery & Psychiatry · 2020 · 268 citations · 42 references

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Abstract

Increased α-synuclein egress in serum neuronal exosomes precedes the diagnosis of Parkinson's disease, persists with disease progression and in combination with clusterin predicts and differentiates Parkinson's disease from atypical parkinsonism.

References

42

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Théry, Kenneth W. Witwer, Elena Aïkawa et al. · Journal of Extracellular Vesicles · 2018 · 10.7K citations · Full text

Staging of brain pathology related to sporadic Parkinson’s disease

Heiko Braak, Kelly Del Tredici, Udo Rüb et al. · Neurobiology of Aging · 2002 · 10.5K citations

, , +6

Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.

Andrew Hughes, S. E. Daniel, Linda Kilford et al. · Journal of Neurology Neurosurgery & Psychiatry · 1992 · 10.3K citations · Full text

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

Katya Rascovsky, John R. Hodges, David S. Knopman et al. · Brain · 2011 · 5.1K citations · Full text

, , +15

Classification of primary progressive aphasia and its variants

Maria‐Luisa Gorno‐Tempini, Argye E. Hillis, Andrew Kertesz et al. · Neurology · 2011 · 5K citations · Full text

, , +18