Concepedia

Direct modifications of the cyclic peptide Polymyxin B leading to analogues with enhanced in vitro antibacterial activity

Pamela Brown, Omar Abdulle, Steven Boakes, Esther Duperchy, Stephen Moss, Mona Simonovic, Steven J. Stanway, Antoinette Wilson, Michael J. Dawson

Bioorganic & Medicinal Chemistry Letters · 2020 · 12 citations · 8 references

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8

<i>N</i>-Halosuccinimide/BF<sub>3</sub>−H<sub>2</sub>O, Efficient Electrophilic Halogenating Systems for Aromatics

G. K. Surya Prakash, Thomas Mathew, Dushyanthi Hoole et al. · Journal of the American Chemical Society · 2004 · 353 citations

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Antimicrobial Activity and Toxicity of the Major Lipopeptide Components of Polymyxin B and Colistin: Last-Line Antibiotics against Multidrug-Resistant Gram-Negative Bacteria

Kade D. Roberts, Mohammad Abul Kalam Azad, Jiping Wang et al. · ACS Infectious Diseases · 2015 · 166 citations · Full text

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Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B

Alejandra Gallardo‐Godoy, Craig Muldoon, Bernd Becker et al. · Journal of Medicinal Chemistry · 2016 · 131 citations · Full text

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Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’

Tony Velkov, Kade D. Roberts, Roger L. Nation et al. · ACS Chemical Biology · 2014 · 126 citations · Full text

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Interactions of Lipopolysaccharide and Polymyxin Studied by NMR Spectroscopy

Jiří Mareš, Sowmini Kumaran, Marina Gobbo et al. · Journal of Biological Chemistry · 2009 · 115 citations · Full text

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