Metabolic engineering of Geobacillus thermoglucosidasius for high yield ethanol production

R. E. Cripps, Kirstin L. Eley, David J. Leak, +6

Metabolic Engineering

BiomanufacturingEngineeringBioenergyBiochemical EngineeringBiotechnology +5

Dissecting Structural and Functional Diversity of the Lantibiotic Mersacidin

Antony N. Appleyard, Shaila Choi, Daniel M. Read, +8

Chemistry & Biology

Bioorganic ChemistryEngineeringAntibacterial ActivityDrug ResistanceMersacidin Variants +15

Biosynthesis of the Putative Siderophore Erythrochelin Requires Unprecedented Crosstalk between Separate Nonribosomal Peptide Gene Clusters

Orestis Lazos, Manuela Tosin, Adrian L. Slusarczyk, +4

Chemistry & Biology

BiosynthesisProtein FunctionProtein AssemblyBiochemistryProtein Folding +6

Design of Next Generation Polymyxins with Lower Toxicity: The Discovery of SPR206

Pamela Brown, Elizabeth Abbott, Omar Abdulle, +11

ACS Infectious Diseases

Organization of the genes encoding the biosynthesis of actagardine and engineering of a variant generation system

Steven Boakes, Jesús Cortés, Antony N. Appleyard, +2

Molecular Microbiology

EngineeringGeneticsBacteriologyGara GeneVariant Generation System +18

Generation of an actagardine A variant library through saturation mutagenesis

Steven Boakes, Tania Ayala, Mark A. Herman, +3

Applied Microbiology and Biotechnology

Combinatorial ChemistryMedicinal ChemistryBiosynthesisBioorganic ChemistryEngineering +8

Organization of the biosynthetic genes encoding deoxyactagardine B (DAB), a new lantibiotic produced by Actinoplanes liguriae NCIMB41362

Steven Boakes, Antony N. Appleyard, Jesús Cortés, +1

The Journal of Antibiotics

BiologyBiosynthesisDeoxyactagardine BNatural SciencesMolecular Biology +7

Antibacterial activity of the novel semisynthetic lantibiotic NVB333 in vitro and in experimental infection models

Steven Boakes, Jason Weiss, M. E. Vinson, +2

The Journal of Antibiotics

Antimicrobial Drug DiscoveryAntimicrobial SusceptibilityMedicineAntibacterial ActivityAntibacterial Agent +7

Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin

Pamela Brown, Omar Abdulle, Steven Boakes, +11

ACS Infectious Diseases

Robust reporter system based on chalcone synthase rppA gene from Saccharopolyspora erythraea

Vasilka Magdevska, Rok Gaber, Dušan Goranovič, +8

Journal of Microbiological Methods

Robust Reporter SystemBiosynthesisEngineeringMolecular BiotechnologyReporter Gene Assay +7