TLR4 activation leads to anti-EGFR therapy resistance in head and neck squamous cell carcinoma.

Houyu Ju, Zhenrong Hu, Yusheng Lu, Yunteng Wu, Liming Zhang, Dongliang Wei, Wei Guo, Weiya Xia, Shuli Liu, Guoxin Ren,

PubMed · 2020 · 22 citations · 28 references

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Abstract

. Out study delineates a crosstalk between EGFR and TLR4 pathways and identified TLR4 as a potential biomarker as well as a therapeutic target in overcoming the resistance to anti-EGFR therapy of HNSCC.

References

28