Synthesis and anti-inflammatory evaluation of new chalcone derivatives bearing bispiperazine linker as IL-1β inhibitors

Thymoquinone attenuates rheumatoid arthritis by downregulating TLR2, TLR4, TNF-α, IL-1, and NFκB expression levels

Sabeen Arjumand, Muhammad Shahzad, Arham Shabbir · Biomedicine & Pharmacotherapy · 2019 · 109 citations · Full text

Medicine, Immunology, Pharmacology +17

Design, synthesis, in-silico and biological evaluation of novel chalcone derivatives as multi-function agents for the treatment of Alzheimer's disease

Zhipei Sang, Keren Wang, Pengfei Zhang et al. · European Journal of Medicinal Chemistry · 2019 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Novel resveratrol-based flavonol derivatives: Synthesis and anti-inflammatory activity in vitro and in vivo

Liu Zeng Chen, Yao Li, Ming Jiao et al. · European Journal of Medicinal Chemistry · 2019 · 79 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Synthesis, biological evaluation, and molecular docking studies of resveratrol derivatives possessing chalcone moiety as potential antitubulin agents

Ban‐Feng Ruan, Xiang Lu, Wei Yao et al. · Bioorganic & Medicinal Chemistry · 2011 · 70 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Synthesis of novel ciprofloxacin analogues and evaluation of their anti-proliferative effect on human cancer cell lines

Suresh Narva, Hunsur Nagendra Nagesh, Kondapalli Venkata Gowri Chandra Sekhar et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6