Synthesis of novel ciprofloxacin analogues and evaluation of their anti-proliferative effect on human cancer cell lines

Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts

Peter Hüssy, Burkhard Tümmler, U. Schomburg · Antimicrobial Agents and Chemotherapy · 1986 · 186 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Ciprofloxacin induces apoptosis and inhibits proliferation of human colorectal carcinoma cells

C. Herold, Matthias Ocker, Marion Ganslmayer et al. · British Journal of Cancer · 2002 · 185 citations · Full text

Medicine, Oncology, Pharmacology +13

Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line.

Olivia Aranha, David P. Wood, F. H. Sarkar · PubMed · 2000 · 123 citations

Medicine, Oncology, Pharmacology +16

Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis

Olivia Aranha, R Grignon, N Freitas Fernandes et al. · International Journal of Oncology · 2003 · 101 citations

Medicine, Oncology, Pharmacology +17

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz et al. · Antimicrobial Agents and Chemotherapy · 1992 · 94 citations · Full text

Medicine, Molecular Biology, Pharmacology +14