Modulating tumor immunity by metronomic dosing of oxaliplatin incorporated in multiple oral nanoemulsion

Calreticulin exposure dictates the immunogenicity of cancer cell death

Michel Obéid, Antoine Tesnière, François Ghiringhelli et al. · Nature Medicine · 2006 · 3K citations

Cancer Immunosurveillance, Calreticulin Exposure, Immunotoxicology +6

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Lionel Apétoh, François Ghiringhelli, Antoine Tesnière et al. · Nature Medicine · 2007 · 2.9K citations

Inflammation, Toll-like Receptors, Cancer Immunosurveillance +12

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

François Ghiringhelli, Lionel Apétoh, Antoine Tesnière et al. · Nature Medicine · 2009 · 1.8K citations · Full text

Inflammation, Cancer Immunosurveillance, Nlrp3 Inflammasome +13

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

Michael R. Elliott, Faraaz B. Chekeni, Paul C. Trampont et al. · Nature · 2009 · 1.6K citations · Full text

Apoptotic Cells Act, Signal Transduction, Phagocytic Clearance +10

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.

Timothy M. Browder, Catherine Butterfield, Birgit M. Kräling et al. · PubMed · 2000 · 1.6K citations

Tumor Biology, Chemoprevention Strategy, Medicine +14