Concepedia

Combined therapy with atorvastatin and atorvastatin-pretreated mesenchymal stem cells enhances cardiac performance after acute myocardial infarction by activating SDF-1/CXCR4 axis.

Xiaqiu Tian, Yuejin Yang, Qing Li, Jun Xu, Peisen Huang, Yuyan Xiong, Xiang‐dong Li, Jin Chen, Kang Qi, Leipei Jiang,

PubMed · 2019 · 20 citations · 36 references

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Concepts

Abstract

MSCs significantly enhanced the targeted recruitment and survival of transplanted MSCs, and resulted in subsequent cardiac function improvement by augmenting SDF-1/CXCR4 signaling.

References

36

Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy

Arman T. Askari, Samuel Unzek, Corey K. Goldman et al. · The Lancet · 2003 · 1.3K citations

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Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic Neovascularization

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Monitoring of Bone Marrow Cell Homing Into the Infarcted Human Myocardium

Michael Hofmann, Kai C. Wollert, Gerd Peter Meyer et al. · Circulation · 2005 · 933 citations · Full text

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Cellular Antioxidant Effects of Atorvastatin In Vitro and In Vivo

Ulrich Laufs, Kirsten Müller, Christian Konkol et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2002 · 591 citations

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SDF‐1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction

Ming Zhang, Niladri Mal, Matthew Kiedrowski et al. · The FASEB Journal · 2007 · 455 citations

, , +14