Concepedia

Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial

Sarah Fidler, Wolfgang Stöhr, Lucy Dorrell, Andrew Lever, Sarah Pett, Sabine Kinloch‐de Loes, Julie Fox, Amanda Clarke, Mark Nelson, John Thornhill,

The Lancet · 2020 · 138 citations · 29 references

DOI

Concepts

References

29

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

Diana Finzi, Joel N. Blankson, Janet D. Siliciano et al. · Nature Medicine · 1999 · 2.1K citations

, , +17

Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

Tae‐Wook Chun, Lucy M. Carruth, Diana Finzi et al. · Nature · 1997 · 2.1K citations

, , +16

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

Nancie M. Archin, Abigail Liberty, Angela D. M. Kashuba et al. · Nature · 2012 · 1.2K citations

, , +12

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

Thomas A. Rasmussen, Martin Tolstrup, Christel R. Brinkmann et al. · The Lancet HIV · 2014 · 641 citations

, , +17

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

James B. Whitney, Alison L. Hill, Srisowmya Sanisetty et al. · Nature · 2014 · 629 citations · Full text

, , +13