A SNP of bacterial blc disturbs gut lysophospholipid homeostasis and induces inflammation through epithelial barrier disruption

Dayuan Zou, Jingwen Pei, Jianfeng Lan, Hong Sang, Hongjuan Chen, Haoliang Yuan, Di Wu, Yuanyuan Zhang, Yufang Wang, Dingyu Wang,

EBioMedicine · 2020 · 37 citations · 49 references

DOIFull text

Open access

Abstract

Our results identified a novel bacterial gene, blc, in E. coli that regulates host gut integrity and immunity. FUND: The Ministry of Science and Technology of China; the National Natural Science Foundation of China; and the Natural Science Foundation of Jiangsu Province.

References

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