Antimalarial drug artesunate is effective against chemoresistant anaplastic thyroid carcinoma via targeting mitochondrial metabolism

mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

Masahiro Morita, Simon‐Pierre Gravel, Valérie Chénard et al. · Cell Metabolism · 2013 · 817 citations · Full text

Mitophagy, Signal Transduction, Mitochondrial Biogenesis +8

Direct control of mitochondrial function by mTOR

Arvind Ramanathan, Stuart L. Schreiber · Proceedings of the National Academy of Sciences · 2009 · 366 citations · Full text

Mitochondrial Biology, Metabolic Remodeling, Mtor Functions +16

Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy.

Steven R. Meshnick, Terrie E. Taylor, Sumalee Kamchonwongpaisan · Microbiological Reviews · 1996 · 291 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Malaria +18

Artesunate Induces ROS-Mediated Apoptosis in Doxorubicin-Resistant T Leukemia Cells

Thomas Efferth, Marco Giaisi, Annette Merling et al. · PLoS ONE · 2007 · 253 citations · Full text

Double genetic disruption of lactate dehydrogenases A and B is required to ablate the “Warburg effect” restricting tumor growth to oxidative metabolism

Maša Ždralević, Almut Brand, Lorenza Di Ianni et al. · Journal of Biological Chemistry · 2018 · 239 citations · Full text

Tumor Biology, Biochemistry, Medicine +11