Cooperation Between MYC and β‐Catenin in Liver Tumorigenesis Requires Yap/Taz

Abstract

Myc and β-catenin show a strong cooperative action in liver carcinogenesis, with Yap and Taz serving as mediators of this effect. These findings warrant efforts toward therapeutic targeting of Yap/Taz in aggressive liver tumors marked by elevated Myc/β-catenin activity.