Publication | Closed Access

Simultaneously predict pharmacokinetic interaction of rifampicin with oral versus intravenous substrates of cytochrome P450 3A/P‑glycoprotein to healthy human using a semi-physiologically based pharmacokinetic model involving both enzyme and transporter turnover

Molecular PharmacologyPharmacokinetic ModelingBiochemistryPharmacological StudyMedicineTransporter TurnoverPharmacotherapyAntimicrobial PharmacokineticsCytochrome P450 3A/p‑glycoproteinPharmacologyPhysiologically-based Pharmacokinetic ModelingPharmacokineticsPharmacodynamic ModelingPharmacokinetic Model