Concepedia

AKT activation by SC79 to transiently re-open pathological blood brain barrier for improved functionalized nanoparticles therapy of glioblastoma

Lijuan Wen, Kai Wang, Fengtian Zhang, Yanan Tan, Xuwei Shang, Yun Zhu, Xueqing Zhou, Hong Yuan, Fuqiang Hu

Biomaterials · 2020 · 34 citations · 41 references

DOI

Concepts

References

41

Transvascular delivery of small interfering RNA to the central nervous system

Priti Kumar, Haoquan Wu, Jodi L. McBride et al. · Nature · 2007 · 1.2K citations

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Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

Samuel A. Jensen, Emily S. Day, Caroline H. Ko et al. · Science Translational Medicine · 2013 · 580 citations · Full text

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Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells

Stacey Watkins, Stefanie Robel, Ian F. Kimbrough et al. · Nature Communications · 2014 · 536 citations · Full text

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Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery <i>via</i> Albumin-Binding Protein Pathways for Antiglioma Therapy

Tingting Lin, Pengfei Zhao, Yifan Jiang et al. · ACS Nano · 2016 · 522 citations

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Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

Yejie Shi, Lili Zhang, Hongjian Pu et al. · Nature Communications · 2016 · 428 citations · Full text

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