Treatment with an immature dendritic cell-targeting vaccine supplemented with IFN-α and an inhibitor of DNA methylation markedly enhances survival in a murine melanoma model

Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684.

J M Kirkwood, M H Strawderman, Marc S. Ernstoff et al. · Journal of Clinical Oncology · 1996 · 2.1K citations

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

Katherine B. Chiappinelli, Pamela L. Strissel, Alexis Desrichard et al. · Cell · 2015 · 1.9K citations · Full text

Chromatin, Epigenetic Change, Dna Methylation +10

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Kelly D. Moynihan, Cary F. Opel, Gregory L. Szeto et al. · Nature Medicine · 2016 · 527 citations · Full text

Immune Evasion, Tumor Immunology, Cancer Immunosurveillance +15

12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?

Jane L. Messina, David Fenstermacher, Steven A. Eschrich et al. · Scientific Reports · 2012 · 411 citations · Full text

Immunoselection in vivo: Independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma

Elke Jäger, Mark Ringhoffer, M. Altmannsberger et al. · International Journal of Cancer · 1997 · 305 citations

Mhc Class, Differentiation Antigen Expression, Immunology +18