Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

Michiru Nishita, Seung‐Yeol Park, Tadashi Nishio et al. · Scientific Reports · 2017 · 15.8K citations · Full text

Tumor Invasiveness, Cytoskeleton, Cancer Biology +20

Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

Engineering, Network Science, P53 Network +5

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

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Tumor Biology, Small-molecule Antagonists, Mdm2-p53 Interaction +14

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

Tumor Biology, Medicine, Rapid Degradation +6

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

Julia Joung, Silvana Konermann, Jonathan S. Gootenberg et al. · Nature Protocols · 2017 · 1.3K citations · Full text

Genetics, Genetic Engineering, Gene Editing +5