Endoscopy International Open · 2020 · 14 citations · 4 references
MedicineOncologySurgeryGastrointestinal OncologyHistopathologySurgical PathologyEndocrine Tumor DiagnosisEndocrine TumorsNeuroendocrine TumorsPancreatic CancerPancreatic DiseasesPancreatic SurgeryEndocrine Neoplasm HistopathologyEndoscopic Ultrasound-guided Fine-needle AspirationHistochemical MarkersImage-guided Fine-needle AspirationPancreatic Neuroendocrine NeoplasmsPancreatic Neuroendocrine Tumor DiagnosisPancreatic Neuroendocrine Tumor ImagingPancreatic Neuroendocrine Tumor Pathology
A 49-year-old woman consulted her general practitioner (GP) regarding epigastric pain that she had experienced for 2 months. Physical examination and laboratory results were unremarkable. An abdominal ultrasound indicated a solid pancreatic tumor, which was confirmed on subsequent CT and MRI. Endoscopic ultrasound (EUS) showed a well-defined heterogeneous, predominantly hypoechoic mass in the pancreatic body, so a neuroendocrine tumor (NET) was suspected. However, EUS-guided fine-needle aspiration (EUS-FNA) was performed and based on (immuno-)histochemical findings, the extremely rare diagnosis of a perivascular epithelioid cell tumor (PEComa) of the pancreas was made. Due to the malignant potential of pancreatic PEComas, laparoscopic left-sided pancreatectomy was performed. We present a case diagnosed by preoperative EUS-FNA highlighting the clinical and endosonographic features which help to distinguish it from its most important differential diagnosis, neuroendocrine tumors (NETs) of the pancreas.
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Clear Cell “Sugar” Tumor of the Pancreas
Giuseppe Zamboni, Maurizio Pea, Guido Martignoni et al. · The American Journal of Surgical Pathology · 1996 · 380 citations