Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human β Cells

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.7K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby et al. · Nature Biotechnology · 2014 · 7.8K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +16

SCENIC: single-cell regulatory network inference and clustering

Sara Aibar, Carmen Bravo González‐Blas, Thomas Moerman et al. · Nature Methods · 2017 · 6.9K citations · Full text

Life Sciences, Bioinformatics, Biology +17

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

A.M. James Shapiro, Jonathan R.T. Lakey, Edmond A. Ryan et al. · New England Journal of Medicine · 2000 · 5.3K citations · Full text

Medicine, Endocrinology, Surgery +16

Differential analysis of gene regulation at transcript resolution with RNA-seq

Cole Trapnell, David G. Hendrickson, Martin Sauvageau et al. · Nature Biotechnology · 2012 · 3.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +16