Short-term GLP-1 receptor agonist exenatide ameliorates intramyocellular lipid deposition without weight loss in ob/ob mice

Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

Matthew J. Armstrong, Piers Gaunt, Guruprasad P. Aithal et al. · The Lancet · 2015 · 2.1K citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +5

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Yasuhiko Minokoshi, Young‐Bum Kim, Odile D. Peroni et al. · Nature · 2002 · 2K citations

Life Sciences, Endocrinology, Physiology +13

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

Gianluca Perseghin, Paola Scifo, Francesco De Cobelli et al. · Diabetes · 1999 · 880 citations

Medicine, Endocrinology, Physiology +17

Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

Simon N. Jacob, Jürgen Machann, K. Rett et al. · Diabetes · 1999 · 641 citations

Medicine, Endocrinology, Diabetology +13

Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice

Shu Lin, T. C. Thomas, LH Storlien · International Journal of Obesity · 2000 · 568 citations

Medicine, Endocrinology, Nutritional Sciences +15