Concepedia

Publication | Open Access

Succinate‐GPR‐91 receptor signalling is responsible for nonalcoholic steatohepatitis‐associated fibrosis: Effects of DHA supplementation

DOIFull Paper Access

58

Citations

19

References

2020

Year

Xuejing Liu, Li Xie, Kuo Du, Chang Liu, Ning‐Ping Zhang, Chen‐Jian Gu, Ying Wang, Manal F. Abdelmalek, Wenyue Dong, Xiuping Liu,
Liver International

Abstract

Succinate accumulation in steatotoic hepatocytes may result in HSC activation through GPR-91 receptor signalling in NASH progression, and the cross-talk between hepatocytes and HSC through GPR-91 signalling is most likely to be the molecular basis of fibrogenesis in NASH.

References

YearCitations

Page 1