Potential Synthetic Adaptogens: V. Synthesis of Cage Monoamines by the Schwenk–Papa Reaction

Abstract

The reduction of cage ketoximes under Schwenk–Papa reaction conditions was studied to establish that the d , l , d - and l -camphor oximes are smoothly reduced to the corresponding amines in high yields. At the same time, d , l -norcamphor and adamantan-2-one oximes undergo partial catalytic deoximation to form a mixture of the corresponding amines and alcohols.