Organic Chemistry Frontiers · 2019 · 18 citations · 77 references
Natural SciencesChemistryCatalysisComputational ChemistryOrganometallic ChemistryCatalyst SynthesisCatalytic MechanismsCatalyst Structure - Activity RelationshipsCatalytic Reaction MechanismsSubstrate ScopeSubstrate Scope Expansion
NHC-catalyzed mild desulfonylation of tosylated aldimines provides efficient access to aryl nitriles with broad substrate scope. DFT calculations demonstrate that the reaction undergoes multiple stepwise processes.
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