Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit

Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes

Yue Wang, Shijie Jin, Yoshifumi Sonobe et al. · PLoS ONE · 2014 · 282 citations · Full text

Medicine, Neurobiology, Neuroscience +17

The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury

Tetsuhiro Higashida, Christian W. Kreipke, José A. Rafols et al. · Journal of neurosurgery · 2010 · 279 citations

Medicine, Neurobiology, Neuroscience +17

Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury

Jian Chen, Zhouguang Wang, Zengming Zheng et al. · Cell Death and Disease · 2017 · 183 citations · Full text

Medicine, Neurobiology, Neuroscience +17

miR-21 improves the neurological outcome after traumatic brain injury in rats

Xintong Ge, Ping Lei, Haichen Wang et al. · Scientific Reports · 2014 · 166 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Sonic Hedgehog Signaling Pathway Mediates Cerebrolysin-Improved Neurological Function After Stroke

Li Zhang, Michael Chopp, D. Meier et al. · Stroke · 2013 · 147 citations

Life Sciences, Neurobiology, Neuroscience +17