<i>Tcf7l2</i> transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus

Abstract

This study provides evidence for a novel and crucial role of Tcf7l2 in the molecular mechanism by which the neurotransmitter identity of glutamatergic thalamic neurons is established. Our findings exemplify a clear case of neurotransmitter identity regulation that is partitioned into initiation and maintenance phases.