Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice

Bingxin Lu, Jianing Zhong, Jianfei Pan, Xiaopeng Yuan, Mingzhi Ren, Liping Jiang, Yuqing Yang, Guisheng Zhang, Dexi Liu, Chunbo Zhang

Journal of Translational Medicine · 2019 · 40 citations · 33 references

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Abstract

These results demonstrate that GDF11 plays an important role in regulating metabolic homeostasis and energy balance and could be a target for pharmacological intervention to treat metabolic disease.

References

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