T618I CSF3R mutations in chronic neutrophilic leukemia induce oncogenic signals through aberrant trafficking and constitutive phosphorylation of the O-glycosylated receptor form

Oncogenic<i>CSF3R</i>Mutations in Chronic Neutrophilic Leukemia and Atypical CML

Julia E. Maxson, Jason Gotlib, Daniel A. Pollyea et al. · New England Journal of Medicine · 2013 · 563 citations · Full text

Medicine, Hematology, Oncology +17

Mechanism of Activation of Protein Kinase JAK2 by the Growth Hormone Receptor

Andrew J. Brooks, Wei Dai, Megan L. O’Mara et al. · Science · 2014 · 415 citations

Life Sciences, Biochemistry, Molecular Biology +17

Regulation of Jak2 through the Ubiquitin-Proteasome Pathway Involves Phosphorylation of Jak2 on Y1007 and Interaction with SOCS-1

Daniela Ungureanu, Pipsa Saharinen, Ilkka Junttila et al. · Molecular and Cellular Biology · 2002 · 258 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A direct role for Met endocytosis in tumorigenesis

Carine Joffre, Rachel Barrow, Ludovic Ménard et al. · Nature Cell Biology · 2011 · 239 citations

Medicine, Cancer Biology, Cell Biology +13

Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis

Jürgen Gent, Peter van Kerkhof, Marcel Roza et al. · Proceedings of the National Academy of Sciences · 2002 · 190 citations

Life Sciences, Biochemistry, Molecular Biology +17