Geniposidic acid ameliorates spatial learning and memory deficits and alleviates neuroinflammation via inhibiting HMGB-1 and downregulating TLR4/2 signaling pathway in APP/PS1 mice

ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion

Yu‐Wen Alvin Huang, Bo Zhou, Marius Wernig et al. · Cell · 2017 · 537 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +7

Endogenous amyloid‐β is necessary for hippocampal synaptic plasticity and memory

Daniela Puzzo, Lucia Privitera, Mauro Fà et al. · Annals of Neurology · 2010 · 302 citations

Life Sciences, Neurobiology, Neuroscience +15

Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome

Michael Weber, Matthew G. Frank, Kevin J. Tracey et al. · Journal of Neuroscience · 2015 · 214 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer’s disease

Barry W. Festoff, Ravi K. Sajja, Patrick Van Dreden et al. · Journal of Neuroinflammation · 2016 · 210 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Induction and subcellular localization of high‐mobility group box–1 (HMGB1) in the postischemic rat brain

Jung‐Bin Kim, Chaemoon Lim, Young‐Mi Yu et al. · Journal of Neuroscience Research · 2007 · 199 citations

Life Sciences, Neurobiology, Neuroscience +16