Tumor organoid–T-cell coculture systems

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

Jesse M. Zaretsky, Ángel García-Díaz, Daniel Sanghoon Shin et al. · New England Journal of Medicine · 2016 · 3.2K citations · Full text

Medicine, Immunology, Oncology +17

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Marc van de Wetering, Hayley E. Francies, Joshua M. Francis et al. · Cell · 2015 · 2.4K citations · Full text

Medicine, Oncology, Gastrointestinal Oncology +9

Organoid Modeling of the Tumor Immune Microenvironment

James T. Neal, Xingnan Li, Junjie Zhu et al. · Cell · 2018 · 1.5K citations · Full text

Life Sciences, Cancer Biology, Immunology +14

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

Yannick Simoni, Étienne Becht, Michael Fehlings et al. · Nature · 2018 · 1.4K citations

Life Sciences, Immunology, Oncology +14

PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors

Alena Gros, Paul F. Robbins, Xin Yao et al. · Journal of Clinical Investigation · 2014 · 1.1K citations · Full text

Life Sciences, Immunology, Oncology +17