Concepedia

MiR-216a accelerates proliferation and fibrogenesis via targeting PTEN and SMAD7 in human cardiac fibroblasts

Jinsong Tao, Jingyi Wang, Chunyu Li, Weiwei Wang, Hao Yu, Jinhui Liu, Xiangqing Kong, Yan Chen

Cardiovascular Diagnosis and Therapy · 2019 · 29 citations · 14 references

DOIFull text

Open access

Abstract

Our study might provide a promising approach for the treatment of HF in the future.

References

14

Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation

Peter A. Kavsak, Richele K. Rasmussen, Carrie G. Causing et al. · Molecular Cell · 2000 · 1.3K citations · Full text

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Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression

Xiaoxu Zhou, Xiujuan Zang, Murugavel Ponnusamy et al. · Journal of the American Society of Nephrology · 2015 · 196 citations · Full text

Atrial Fibrillation Induces Myocardial Fibrosis Through Angiotensin II Type 1 Receptor–Specific Arkadia-Mediated Downregulation of Smad7

Xuyu He, Xiuren Gao, Longyun Peng et al. · Circulation Research · 2010 · 155 citations · Full text

MiR-216a: a link between endothelial dysfunction and autophagy

Rossella Menghini, Viviana Casagrande, Arianna Marino et al. · Cell Death and Disease · 2014 · 143 citations · Full text

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Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs

Christine Voellenkle, Jeroen van Rooij, Alessandro Guffanti et al. · RNA · 2012 · 131 citations · Full text

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