CXCL12 is involved in α-synuclein-triggered neuroinflammation of Parkinson’s disease

Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease

Wei Zhang, Tongguang Wang, Zhong Pei et al. · The FASEB Journal · 2005 · 1.3K citations

Neurodegenerative Diseases, Resident Microglia, Nadph Oxidase +14

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

Alexander Gerhard, Nicola Pavese, Gary Hotton et al. · Neurobiology of Disease · 2005 · 1.2K citations · Full text

Neuroimaging Biomarkers, Vivo Imaging, Idiopathic Parkinson +8

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Richard D. Gordon, Eduardo A. Albornoz, Daniel C. Christie et al. · Science Translational Medicine · 2018 · 839 citations

Mitophagy, Immunology, Cell Death +27

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

Changyoun Kim, Dong Hwan Ho, Ji‐Eun Suk et al. · Nature Communications · 2013 · 807 citations · Full text

Inflammation, Neurodegenerative Diseases, Endogenous Agonist +11

Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

Kazuhiro Imamura, Nozomi Hishikawa, Makoto Sawada et al. · Acta Neuropathologica · 2003 · 800 citations

Neurodegenerative Diseases, Medicine, Immunology +8