Population Life-course exposure to health effects model (PLETHEM): An R package for PBPK modeling

Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia [published erratum appears in Blood 1992 Aug 1;80(3):855]

Josephia R. Muindi, SR Frankel, WH Jr Miller et al. · Blood · 1992 · 411 citations · Full text

Medicine, Hematology, Pharmacology +10

Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia [published erratum appears in Blood 1992 Aug 1;80(3):855]

Josephia R. Muindi, SR Frankel, WH Jr Miller et al. · Blood · 1992 · 320 citations · Full text

Medicine, Hematology, Pharmacology +10

<b>httk</b>: <i>R</i> Package for High-Throughput Toxicokinetics

Robert G. Pearce, R. Woodrow Setzer, Cory L Strope et al. · Journal of Statistical Software · 2017 · 309 citations · Full text

Pharmacy, Toxicology, Mechanisms Of Toxicity +6

Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted<i>In Vitro</i>Bioactivity to Inform Chemical Toxicity Testing

Barbara A. Wetmore, John F. Wambaugh, Brittany Allen et al. · Toxicological Sciences · 2015 · 233 citations · Full text

Pharmacy, Toxicology, Dose-response Modeling +16

High-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project

John F. Wambaugh, R. Woodrow Setzer, David M. Reif et al. · Environmental Science & Technology · 2013 · 224 citations

Pharmacy, Environmental Sciences, Toxicology +16