Curcumin analog, WZ37, promotes G2/M arrest and apoptosis of HNSCC cells through Akt/mTOR inhibition

Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of <scp>AKT</scp>/<scp>mTOR</scp> pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation

Yingqiang Shen, Ana Guerra‐Librero, Beatriz I. Fernández-Gil et al. · Journal of Pineal Research · 2017 · 170 citations

Medicine, Oncology, Pharmacology +17

ROS generation mediates the anti-cancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer

Peng Zou, Junru Zhang, Yiqun Xia et al. · Oncotarget · 2015 · 156 citations · Full text

Medicine, Oncology, Pharmacology +16

Association of Quantitative Metastatic Lymph Node Burden With Survival in Hypopharyngeal and Laryngeal Cancer

Allen S. Ho, Sungjin Kim, Mourad Tighiouart et al. · JAMA Oncology · 2017 · 130 citations · Full text

Medicine, Oncology, Surgery +17

A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells

Zahoor A. Wani, Santosh Kumar Guru, Alka Rao et al. · Food and Chemical Toxicology · 2015 · 90 citations

Life Sciences, Oncology, Pharmacology +14

Curcumin induces G2/M cell cycle arrest and apoptosis of head and neck squamous cell carcinoma<i>in vitro</i>and<i>in vivo</i>through ATM/Chk2/p53-dependent pathway

An Hu, Jingjuan Huang, Jingfei Zhang et al. · Oncotarget · 2017 · 89 citations · Full text

Medicine, Oncology, Pharmacology +16