Concepedia

HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease

Maria Anele Romeo, Maria Saveria Gilardini Montani, Aurelia Gaeta, Gabriella D’Orazi, Alberto Faggioni, Mara Cirone

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2019 · 46 citations · 24 references

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24

Tau is essential to β-amyloid-induced neurotoxicity

Mark Rapoport, Hana N. Dawson, Lester I. Binder et al. · Proceedings of the National Academy of Sciences · 2002 · 802 citations · Full text

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Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

Ben Readhead, Jean‐Vianney Haure‐Mirande, Cory C. Funk et al. · Neuron · 2018 · 729 citations · Full text

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Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

William A. Eimer, Deepak Kumar Vijaya Kumar, Nanda Kumar N. Shanmugam et al. · Neuron · 2018 · 675 citations · Full text

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Phosphorylation of different tau sites during progression of Alzheimer’s disease

Joerg Neddens, Magdalena Temmel, Stefanie Flunkert et al. · Acta Neuropathologica Communications · 2018 · 382 citations · Full text

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Autophagy failure in <scp>A</scp>lzheimer's disease and the role of defective lysosomal acidification

Devin M. Wolfe, Ju‐Hyun Lee, Asok Kumar et al. · European Journal of Neuroscience · 2013 · 346 citations · Full text

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