Concepedia

Circulating levels of ATP is a biomarker of HIV cognitive impairment

Stephani Velasquez, Lisa Prevedel, Silvana Valdebenito, Anna Górska, Mikhail Y. Golovko, Nabab Khan, Jonathan D. Geiger, Eliseo A. Eugenín

EBioMedicine · 2019 · 47 citations · 71 references

DOIFull text

Open access

Abstract

We propose that circulating levels of ATP could predict CNS compromise and lead to the breakthroughs necessary to detect and prevent brain compromise in the HIV-infected population.

References

71

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy

Robert K. Heaton, David B. Clifford, Donald Franklin et al. · Neurology · 2010 · 2.3K citations · Full text

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

François Ghiringhelli, Lionel Apétoh, Antoine Tesnière et al. · Nature Medicine · 2009 · 1.8K citations · Full text

, , +13

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

Michael R. Elliott, Faraaz B. Chekeni, Paul C. Trampont et al. · Nature · 2009 · 1.6K citations · Full text

, , +10

Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor

Pablo Pelegrı́n, Annmarie Surprenant · The EMBO Journal · 2006 · 1.4K citations · Full text

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

Faraaz B. Chekeni, Michael R. Elliott, Joanna K. Sandilos et al. · Nature · 2010 · 1.1K citations

, , +17