Cell Therapy in Burn Repair

Abstract

Skin replacement has been a challenging task in wound healing resulted from burn. Theapplication of laboratory based tissue expansion techniques is a potential solution tothe problem of surface area cover. Fortunately, considerable progress has been madein approaches to allograft and autograft skin transplantation in order to replace skintemporarily or permanently. Despite of this progress, development of new treatments forburn victims are still a problem in cultured skin grafts. Hair follicles, sweat glands and otherfeatures of normal skin are absent in cultured skin. Scientists believe that Stem cells withunique characteristics including self renewal and differentiation potential offer a possibleway for reconstruction of some structures within the wound. So, enhanced understandingof stem cell potentials may help develop novel therapies to overcome the problems inwound healing.