Publication | Open Access
Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma
18
Citations
22
References
2019
Year
Potential Therapeutic TargetTumor BiologyKey Points Ube2tHematological MalignancyMedicineHomologous RecombinationImmunologyMultiple MyelomaMultiple Myeloma CellsRadiation OncologyCancer BiologyCell BiologyCancer ResearchMyeloid Neoplasia
Key Points UBE2T is frequently amplified and/or overexpressed and is required for homologous recombination activity in multiple myeloma cells. UBE2T is a potential therapeutic target to increase chemosensitivity in multiple myeloma cells.
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