Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Shruti Bhatt, Marissa S. Pioso, Elyse A. Olesinski, +20

Cancer Cell

Hematological MalignancyBh3 MimeticsMitochondrial FunctionMixed-phenotype Acute LeukemiaAcute Myeloid Leukemia +9

Impaired T- and NK-cell reconstitution after haploidentical HCT with posttransplant cyclophosphamide

Benedetta Rambaldi, Haesook T. Kim, Carol Reynolds, +15

Blood Advances

Cell TherapyImmunologyImmunotherapyChronic GvhdBone Marrow Failure +14

Interactions of the Hdm2/p53 and Proteasome Pathways May Enhance the Antitumor Activity of Bortezomib

Melissa Ooi, Patrick Hayden, Vassiliki Kotoula, +14

Clinical Cancer Research

Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome

Jagannath Pal, Robert C. Bertheau, Leutz Buon, +11

Oncogene

ChromatinGenome InstabilityChromatin RemodelingGeneticsGenomic Evolution +7

Molecular and Cellular Effects of NEDD8-Activating Enzyme Inhibition in Myeloma

Douglas W. McMillin, Hannah M. Jacobs, Jake Delmore, +10

Molecular Cancer Therapeutics

Hematological MalignancyBiochemistryNatural SciencesMalignant Blood DisorderImmunology +11

Dysregulated APOBEC3G causes DNA damage and promotes genomic instability in multiple myeloma

Srikanth Talluri, Mehmet Samur, Leutz Buon, +6

Blood Cancer Journal

Targeting homologous recombination and telomerase in Barrett’s adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth

Rongzhu Lu, Jagannath Pal, Leutz Buon, +9

Oncogene

Molecular and cellular effects of multi‐targeted cyclin‐dependent kinase inhibition in myeloma: biological and clinical implications

Douglas W. McMillin, Jake Delmore, Joseph Negri, +12

British Journal of Haematology

RAD51 Is Implicated in DNA Damage, Chemoresistance and Immune Dysregulation in Solid Tumors

Chengcheng Liao, Srikanth Talluri, Jiangning Zhao, +6

Cancers

Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma

David A. Alagpulinsa, Subodh Kumar, Srikanth Talluri, +7

Blood Advances

Potential Therapeutic TargetTumor BiologyKey Points Ube2tHematological MalignancyMedicine +9