PubMed · 2018 · 121 citations · 48 references
Open access
Life SciencesMicrobiologyBacteriologyMedical MicrobiologyMicrobiome ResearchGut MicrobiomeGut MicrobiotaMicrobial Community DynamicsMicrobial Community ProfilingMicrobiome CompositionMicrobiome DiversityBacterial Community DynamicsBacterial Community EcologyFecal Microbiome AnalysisGut Microbiota CompositionHypervariable Region AnalysisInterindividual VariationLung MicrobiomePrincipal Coordinates Analysis
< 0.05). Most notably, correlations between certain specific bacteria and serum inflammatory biomarkers were identified. Our findings demonstrated an altered bacterial community in patients with lung cancer, providing a significant step in understanding the relationship between gut bacteria and lung cancer. To our knowledge, this is the first study to evaluate the correlations between certain specific bacteria and inflammatory indicators. To better understand this relationship, further studies should investigate the underlying mechanisms of gut bacteria in lung cancer animal models.
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UPARSE: highly accurate OTU sequences from microbial amplicon reads
R. C. Edgar · Nature Methods · 2013 · 17.3K citations
Metagenomic biomarker discovery and explanation
Nicola Segata, Jacques Izard, Levi Waldron et al. · Genome biology · 2011 · 16.7K citations · Full text
FLASH: fast length adjustment of short reads to improve genome assemblies
Tanja Magoč, Steven L. Salzberg · Bioinformatics · 2011 · 15.7K citations · Full text
UCHIME improves sensitivity and speed of chimera detection
R. C. Edgar, Brian J. Haas, José C. Clemente et al. · Bioinformatics · 2011 · 15.5K citations · Full text
Life Sciences, Biology, Microbiology +17