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Role of Maternal Age and Pregnancy History in Risk of Miscarriage: Prospective Register-based Study
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2019
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Prospective Register-based StudyFertilityReproductive HealthGynecologyPreterm Birth PredictionPreterm Birth PreventionReproductive EpidemiologyHigh-risk PregnancyNorwegian WomenObstetricsPublic HealthPregnancy HistoryMaternal Cardiovascular OutcomeMaternal AgeMaternal ComplicationMaternal HealthPlacental DiseasePerinatal EpidemiologyEpidemiologyMiscarriage RiskPregnancyMedicineWomen's Health
( BMJ . 2019;364:I869) Miscarriage is unfortunately a relatively common pregnancy outcome. Various studies have reported that 12% to 15% of pregnancies end in miscarriage. However, these rates may not be accurate as some women experience miscarriage without ever realizing they were pregnant and differences exist among studies regarding the definition of miscarriage versus stillbirth. Several risk factors for miscarriage have been reported, but maternal age seems to have the strongest association. The youngest mothers have a slightly increased risk while older women have a much greater risk than younger women. There might also be an association between previous pregnancy complications and miscarriage risk. This population-based study aimed to evaluate the rate of miscarriage and its association with maternal age and pregnancy history among Norwegian women.