Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo[1,5-a]pyrimidines as novel larotrectinib analogs

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

Life Sciences, Cell Biology, Apoptosis +14

ProTox-II: a webserver for the prediction of toxicity of chemicals

Priyanka Banerjee, Andreas Eckert, Anna K. Schrey · Nucleic Acids Research · 2018 · 3.1K citations · Full text

Pharmacy, Medicinal Chemistry, Toxicology +14

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion–Positive Solid Tumors

Alexander Drilon, Ramamoorthy Nagasubramanian, James F. Blake et al. · Cancer Discovery · 2017 · 433 citations · Full text

Medicine, Oncology, Pharmacology +16

Synthesis and anti-tumor activities of some new pyridines and pyrazolo[1,5-a]pyrimidines

Osama M. Ahmed, Mahmoud A. Mohamed, Rasha R. Ahmed et al. · European Journal of Medicinal Chemistry · 2009 · 137 citations

Pharmacy, Medicinal Chemistry, Oncology +13

Synthesis of pyrazolo[1,5-a]pyrimidine linked aminobenzothiazole conjugates as potential anticancer agents

Ahmed Kamal, Jaki R. Tamboli, Veena Nayak et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 90 citations

Medicine, Medicinal Chemistry, Pharmacology +10