Zinc supplementation protects against diabetic endothelial dysfunction via GTP cyclohydrolase 1 restoration

IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045

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Cardiac Metallothionein Induction Plays the Major Role in the Prevention of Diabetic Cardiomyopathy by Zinc Supplementation

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Proteasome-Dependent Degradation of Guanosine 5′-Triphosphate Cyclohydrolase I Causes Tetrahydrobiopterin Deficiency in Diabetes Mellitus

Jian Xu, Yong Wu, Ping Song et al. · Circulation · 2007 · 193 citations

Life Sciences, Biochemistry, Molecular Biology +17

Effects of zinc supplementation on the plasma glucose level and insulin activity in genetically obese (ob/ob) mice

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Zinc plays a key role in human and bacterial GTP cyclohydrolase I

Günter Auerbach, Anja Herrmann, Andreas Bracher et al. · Proceedings of the National Academy of Sciences · 2000 · 136 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14