A near-infrared fluorescent probe for the ratiometric detection and living cell imaging of β-galactosidase

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.3K citations · Full text

Replicative Senescence, Developmental Biology, Aging +14

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

Florence Debacq‐Chainiaux, Jorge D. Erusalimsky, Judith Campisi et al. · Nature Protocols · 2009 · 1.6K citations · Full text

Lifespan Extension, Aging, Senescence-associated Beta-galactosidase +8

Plasmonic ELISA for the ultrasensitive detection of disease biomarkers with the naked eye

Roberto de la Rica, Molly M. Stevens · Nature Nanotechnology · 2012 · 863 citations

Engineering, Allergy, Medicine +12

Characterization of a human ovarian carcinoma cell line (NIH:OVCAR-3) with androgen and estrogen receptors.

Thomas C. Hamilton, Robert C. Young, Wilma M. McKoy et al. · PubMed · 1983 · 543 citations

Estrogen Receptors, Endocrine Oncology, Medicine +14

Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands

Andreas Becker, Carsten Hessenius, Kai Licha et al. · Nature Biotechnology · 2001 · 519 citations

Engineering, Oncologic Imaging, Biomedical Imaging +5