The prediction of the operating conditions on the permeate flux and on protein aggregation during membrane processing of monoclonal antibodies

Bioprocess membrane technology

Robert van Reis, Andrew L. Zydney · Journal of Membrane Science · 2007 · 756 citations

Biomanufacturing, Engineering, Membrane Process +6

Protein Folding Intermediates and Inclusion Body Formation.

Anna Mitraki, Jonathan King · Nature Biotechnology · 1989 · 423 citations

Protein Assembly, Protein Folding, Natural Sciences +4

Response of a concentrated monoclonal antibody formulation to high shear

Jared S. Bee, Jennifer L. Stevenson, Bhavya Mehta et al. · Biotechnology and Bioengineering · 2009 · 197 citations · Full text

Immunocytochemical Technique, Engineering, Fluid Mechanics +16

Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations

James D. Andya, Chung C. Hsu, Steven J. Shire · AAPS PharmSci · 2003 · 163 citations · Full text

Monoclonal Antibody Self-Association, Cluster Formation, and Rheology at High Concentrations

Wayne Lilyestrom, Sandeep Yadav, Steven J. Shire et al. · The Journal of Physical Chemistry B · 2013 · 157 citations

Immunology, Solution Saxs Characterization, Protein Phase Separation +20