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Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)

Michał Marzec, Qian Zhang, Ami Goradia et al. · Proceedings of the National Academy of Sciences · 2008 · 723 citations · Full text

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Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-γ and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway

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