Concepedia

Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations

Amirhossein Ghanbari Niaki, Jaya Sarkar, Xinyi Cai, Kevin Rhine, Velinda Vidaurre, Brian Guy, Miranda N. Hurst, Jong Chan Lee, Hye Ran Koh, Lin Guo,

Molecular Cell · 2019 · 171 citations · 39 references

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39

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

Amandine Molliex, Jamshid Temirov, Jihun Lee et al. · Cell · 2015 · 2.8K citations

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Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Caroline Vance, Boris Rogelj, Tibor Hortobágyi et al. · Science · 2009 · 2.6K citations · Full text

, , +17

Mutations in the <i>FUS/TLS</i> Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

Thomas J. Kwiatkowski, Daryl A. Bosco, Aurélie Leclerc et al. · Science · 2009 · 2.6K citations

, , +14

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

Jie Wang, Jeong‐Mo Choi, Alex S. Holehouse et al. · Cell · 2018 · 2.2K citations · Full text

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Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

Yuan Lin, David S.W. Protter, Michael K. Rosen et al. · Molecular Cell · 2015 · 1.7K citations · Full text

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