The protein tyrosine phosphatase PTPRJ/DEP-1 contributes to the regulation of the Notch-signaling pathway and sprouting angiogenesis

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Darren A.E. Cross, Dario R. Alessi, Philip Cohen et al. · Nature · 1995 · 5.2K citations

Signal Transduction, Molecular Physiology, Biochemistry +10

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

Holger Gerhardt, Matt Golding, Marcus Fruttiger et al. · The Journal of Cell Biology · 2003 · 2.9K citations · Full text

Angiogenesis, Developmental Biology, Ophthalmology +14

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

Mats Hellström, Li-Kun Phng, Jennifer J. Hofmann et al. · Nature · 2007 · 1.7K citations

Lineage Plasticity, Signal Transduction, Developmental Biology +9

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

Irene Noguera‐Troise, Christopher Daly, Nicholas Papadopoulos et al. · Nature · 2006 · 1K citations

Angiogenesis, Non-productive Angiogenesis, Medicine +8

Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia

Jennifer D. Stone, Ahuva Itin, Tamir Alon et al. · Journal of Neuroscience · 1995 · 1K citations · Full text

First Astrocytes, Developmental Biology, Angiogenesis +14