Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium

Abstract

Maternal GDM was associated with lower cord blood methylation levels within two regions, including the promoter of <i>OR2L13</i>, a gene associated with autism spectrum disorder, and the gene body of <i>CYP2E1</i>, which is upregulated in type 1 and type 2 diabetes. Future studies are needed to understand whether these associations are causal and possible health consequences.