Food Science and Biotechnology · 2019 · 45 citations · 29 references
AgricultureNutritionNutritional SciencesClinical NutritionHuman NutritionObesity PreventionBody Composition ChangesDietary ManagementMedical Nutrition TherapyObesity ManagementWeight LossWeight ManagementBody Composition MeasurementBody Fat PercentageBody Weight RegulationDietary Therapy For ObesityEvidence-based Herbal SafetyObesity TreatmentPlacebo-controlled Efficacy AssessmentWeight Management Through Diet
Steamed ginger ethanolic extract (SGE) is a product with a high 6-shogaol contents and is thought to be more potent than other ginger products. We conducted a 12-week, randomized, double-blind, placebo-controlled clinical trial to determine the effects of SGE on weight and body fat loss. Eighty healthy obese participants were recruited and randomly divided into the SGE and placebo groups. The outcome measures comprised indicators of efficacy (body weight, body mass index, body composition, and blood markers) and safety. Following the supplementation period, mean body weight, body mass index, and body fat level were significantly lower in the SGE group than in the placebo group. No clinically significant changes were observed for any safety parameter. These results suggest that SGE is a potent anti-obesity agent that does not cause significant side effects. Therefore, SGE supplementation combined with lifestyle modification could be effective in the management of body weight and fat mass.
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Srinivas Nammi, Satyanarayana Sreemantula, Basil D. Roufogalis · Basic & Clinical Pharmacology & Toxicology · 2009 · 153 citations